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J Clin Endocrinol Metab 105(4):e963e972 Poor SR et al (2021) Metformin a potential pharmacological strategy in late onset Alzheimers disease treatment

Los investigadores deben consultar la literatura primaria para concentraciones especficas de su modelo experimental

If you're interested in giving it a go, I'd suggest doing a quick patch test (as with all new topical products) before committing fully, to minimise any potential irritation