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It happens when we metabolize our food to make energy

After 72 hr, excess media was removed, and cells were washed with amphibian strength PBS (APBS), and then stained with 50 M mBCI in 70% L15 media for 1 hour (31)

hypothesized that elevated triglyceride (TG) levels could function both as a biomarker for major depression and as a contributor to its pathogenesis, possibly via dual pathways involving metabolic dysfunction and neuroinflammation ( In addition, ketone body (KB), a metabolite of TG in the liver, may also influence MDD (102, 103)

Some of the proposed pathophysiological mechanisms that have been proposed to account for the relationship between UPF, as well as the risk of mood disorders such as depression, include genetically based factors, including the MC4R gene, CRY1 gene, and Cav1 gene, which are associated with an elevated risk of developing depression (60)