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Gonzalez might as well have been given the green light at this point

This difference is reflected in the geometric standard deviations (GSDs), ranging from 1.57 to 1.79, that were on average 5.4% higher for the marijuana smoke size distributions than those of tobacco smoke

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Nicotine's weight effects appear to result especially from the drug's stimulation of 34 nicotine acetylcholine receptors (nAChRs), which are located on pro-opiomelanocortin (POMC) neurons in the arcuate nucleus (ARC), leading to activation of the melanocortin circuit, which is associated with body weight