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doi: 10.1016/0098-8472(87)90059-1 7 BensonN

3.6 SNS and insulin resistance Acute increases in plasma insulin (within the physiological range) stimulated a dose-dependent increase in SNS activity in normal subjects, as demonstrated by increased NE plasma concentrations and microneurographic studies (Rowe et al., 1981), whereas clinical trials in normal volunteer subjects showed that NE infusions cause insulin resistance (Lembo et al., 1994

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5G) were significantly abolished by SERPINB2 depletion