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In the lung, NLRP3-driven cytokine release recruits neutrophils and macrophages, fueling the transition from acute pneumonitis to fibrosis

To reconstitute: For patients 1 year to 17 years of age, for the 20 mg vial: draw up 5 mL of 0.9% Sodium Chloride Injection, USP, further diluting to a final volume of 50 mL

Transglutaminase 2 crosslinks the glutathione S-transferase tag, impeding proteinprotein interactions of the fused protein

Preclinical research suggests it may support the bodys recovery efforts by promoting angiogenesis, encouraging cellular migration, assisting with tissue remodeling, and helping regulate inflammation