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Phenobarbital will function synergistically with benzodiazepines, which could promote excessive sedation

In all models, other determinants of depressive symptoms included sex, education, chronic disease, BMI, antidepressant use at baseline, subthreshold depressive symptoms and vitamin D status as reported previously (Reference Briggs, McCarroll and OHalloran20)

Those with a deficiency in vitamin 12 often have lower bone density, especially women, which can lead to weaker bones and osteoporosis

Moreover, methylcobalamin has been considered for its potential neuroprotective effects, potentially offering benefits in neurological diseases by promoting nerve regeneration and maintenance of the myelin sheath