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At the cellular level, sepsis produces ROS and RNS that further activate inflammatory transcription factors, affecting the endothelium and microvascularization

J Fish Dis 35(5):321334 Joshi B, Chatterji A, Bhonde R (2002) Long-term in vitro generation of amoebocyte from the Indian horseshoe crab Tachypleus Gigas (Muller)