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HIP alters the nanoclusters hydrophobicity and suspendability in organic solvents without changing its molecular structure nor deteriorating its photoluminescence properties (In fact HIP may enhance the photoluminescence of NCs by shell rigidification mechanism) 38

Glutathione reductase (GR), an NADPH-dependent enzyme, continuously regenerates reduced glutathione (GSH) from its oxidized form (GSSG), thereby maintaining the intracellular reducing environment required for effective antioxidant defense, proper enzymatic activity, and redox-dependent signaling pathways [36]

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Trends in use over time are complicated by multiple means of acquiring the drug: through administration by physicians in clinics and hospitals and by caregivers using over-the-counter formulations at home