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Kala SV, Neely MW, Kala G, Prater CI, Atwood DW, Rice JS, Liebermann MW: The MRP2/cMOAT transporter and arsenic-glutathione complex formation are required for biliary excretion of arsenic

The disclosure further relates to a pharmaceutical composition comprising an antibodydrug conjugate as disclosed herein, in combination with one or more pharmaceutical acceptable excipient, diluent or carrier, optionally comprising other active ingredients, for example anti-cancer drugs or immunotherapeutic drugs such as immune checkpoint inhibitors

evaluated ebselen and a collection of its derivatives as inhibitors of the PL pro , leading to identification of inhibitors with IC 50 values in the nanomolar range 38

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