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Description

K., Hutchison, K., Dang, W

132 de AndrsF.Sosa-MacasM.LlerenaA

Because of the less significant correlations between the extent of A depositions and either degree of synapse pathology, neuronal loss or dementia, and also of all the negative results of the anti-A clinical trials so far in the patients with Alzheimers disease, it seems prudent to conclude that the amyloid hypothesis has become unreliable (Pimplikar et al., 2010