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Patients are usually advised to take: A high-potency multivitamin and mineral supplement Vitamin B12 (oral high-dose or intramuscular hydroxocobalamin, depending on absorption) Vitamin D and calcium combined Iron , particularly in women of childbearing age Adhering to these supplementation regimens and attending follow-up appointments is one of the most effective ways to prevent nutritional neuropathy after surgery

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Interestingly, this effect was independent of patients sex, MGMT methylation, p53 mutations or EGFR status