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Furthermore, PGC-1, a key regulator of mitochondrial biogenesis, protects against PD symptoms 30 , as PGC-1 knockout mice are more susceptible to MPTP-induced damage 31

For this purpose, 4-HNE (150 M) was conjugated to L-Lysine (900 M) in PBST for 6 h at room temperature

We aim to pose a perspective for targeting the disease-associated glia to ameliorate the symptoms and revert the disease phenotypes and senescence for human wellness

MSC therapy for colitis focuses on inhibiting colonic macrophages, reducing pro-inflammatory cytokine levels, and inhibiting the NF-B pathway, particularly following inflammation (Yang et al., 2015)