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Since January 2002, 48 states have implemented more than 100 cigarette tax increases

Just 10 years short of reaching a century of service, Demerara Tobacco Company Limited (DEMTOCO) celebrated its 90th anniversary celebration, in which the company singled out the positive efforts of the Private Sector Commission (PSC) of Guyana and the decisive steps taken in combating illicit trade, through the establishment of the Illicit Trade Desk initiative

This is partly due to the overlapping neurobiological mechanisms in addiction, where nicotine alters brain chemistry, accelerating the reward response system, which makes other substances more appealing