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Metabolic Regulation and Fat Metabolism IGF-1 plays important roles in lipid metabolism and energy homeostasis through effects on both fat storage and utilization

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Benefits & Side Effects (Research Context) Observed / Investigated Effects Increased weight gain and nitrogen retention in certain animal models under specific conditions Growth support in models with reduced renal mass (dosedependent protocols studied) Safety Signals / Constraints Biodistribution work suggests rapid internalization/catabolism after receptor binding and fast clearance characteristics in certain setups