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This is corroborated by evidence that intradermal administrations of MSCs in mouse models reduce local inflammatory cytokines without altering systemic cytokine profiles [50]

Li, Q., Gao, Z., Chen, Y

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This results in the formation of Gasdermin D-mediated pores and the violent release of biologically active IL-1, IL-18, and DAMPs ( Salmonella -induced tumor cell death and microenvironment remodeling are shown in Figure 3