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Adding a term to allow a curvilinear model did not improve the fit nor differ from linear models (see supplementary figures 8-10)

Transmission electron microscopy (TEM) of tissues Sciatic nerves were surgically extracted from adult rats and were immediately fixed in 2.5% glutaraldehyde with 0.1M cacodylate buffer, followed by post-fixation in 1% osmium tetroxide, ensuring the preservation of cellular ultrastructure