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Laboratory rats were acclimated for 5 days and randomly assigned to their respective treatment group

Inhibition of lipogenesis AOD-9604 not only breaks down existing fat, but also brakes the formation of new fat

To examine the incorporation of GSH-derived cysteine into downstream pathways, we used an inverse stable-isotope labelling approach 34,35

The inactivation or silencing of Gpx4 gene expression can result in the death of the embryo, possibly due to developmental defects in the brain ( GPX4 are associated with sedaghatnia-type spondylometaphyseal chondrodysplasia, which causes bone, heart, and brain abnormalities and increased cell death ( c -Gys-GSH redox axis and NRF2 signaling pathways