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siRNA-mediated targeting of FUS or CIITA significantly reduced the transcription of MHCII genes (HLA class II, DR alpha (DRA), HLA class II, DR beta 1 (DR1), CD74) and decreased HLA-DR surface expression following IFN- stimulation, without affecting MHCI components, such as HLA-A or NOD-like receptor family CARD domain containing 5 (NLRC5)

What Does the SpectraCell Analysis Test Measure

Moreover, in vitro cultures offer additional advantages due to their ease of handling, allowing them to be modulated using various treatments 7,8

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