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Research shows that TA1 enhances the expression of IL2 receptors and supports the proliferation of helper T cells

In excitotoxicity Ca 2+ uniporter acts as a mediator of death-signal, induced by loss of mitochondrial membrane potential (MMP), but can also serve a pro-survival role through neuroprotective Ca 2+ signaling stemming from synaptic activity (Qiu et al., 2013