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[7] He tapped Greg Nicotero, who had collaborated on several projects, including In the Mouth of Madness (1994) and Vampires (1998), and Howard Berger, who had also earlier worked on John Carpenter's Ghosts of Mars in 2001, as special makeup effects artists

Carbon monoxide binds to haemoglobin (the oxygen-carrying component in red blood cells), resulting in a much stable complex than haemoglobin bound with oxygen or carbon dioxidethe result is permanent loss of red blood cell functionality causing reduced oxygen carrying capacity of blood

The smoking cabin is a solution to prevent second-hand smoke

When Tonys mother (Miriam Colon)a bone thrown to the moralistsgoes through the standard poor-but-proud speech, telling him how worthless he is, the episode has an echo-chamber effect