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Il intervient dans de nombreux processus biochimiques

Ozbudak, E

COX-2 converts AA into prostaglandin-H2 (PGH 2 ), which is then metabolized into PGD 2 , PGE 2 , PGI 2 , or thromboxane-A 2 (TXA 2 ), by the enzymes prostaglandin-D2 synthase ( Ptgds ), PGE synthase ( Ptges ), prostaglandin-I2 synthase ( Ptgis ), and thromboxane-A synthase 1 ( Tbxas1 ), respectively