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*Correspondence: Yanqin Guo, [email protected]

Several studies have identified various sources of ROS and RNS in IBD, including neutrophils, macrophages, and inflamed intestinal tissue (2426)

In an in-vivo study, it has been seen that mitochondrial ROS can have less detrimental effects in worms by increasing their lifespan while increased level of ROS in cytoplasmic may have less lifespan of worms [43]