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Economic Impact: Higher taxes risk worsening smuggling and revenue loss

67 68 Helping Californians quit vapes only helps us get one step closer to ending Big Tobaccos epidemic

The global industrial hemp market is expected to explode to over $10 billion dollars by 2025, while the market for CBD will jump from nearly $600 million in 2018 to $22 billion by 2022

14) that can signal the release of neurotransmitters such as dopamine, norepinephrine, acetylcholine, GABA, and glutamate involved in reward pathways, transmission at the neuromuscular junction, and cognition (Figures 2, 3) [Figure 2) [ FIGURE 2 FIGURE 3 Brain imaging studies have demonstrated that nicotine acutely increases the activity in the visual system, PFC, and thalamus which are consistent with activation of the corticobasal ganglia-thalamic brain circuits [Figure 4) [ FIGURE 4 While electronic cigarettes (e-cigarettes) do not produce combusted smoke, they do deliver an aerosol containing nicotine and other tobacco-related compounds [26]