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Strong recommendation, high certainty Recommendation 6 Combination nicotine replacement therapy (NRT) (ie patch and oral form) accompanied by behavioural support is more effective than NRT monotherapy accompanied by behavioural support, and should be recommended to people who smoke who have evidence of nicotine dependence

To ensure that the market introduction of a cMRTP benefits the population as a whole, one has to take into account how the product will be used by smoker taking into account non-smokers [9]

Thoughtfully yours, Jeff Skipper

The use of cigarettes is increasing in almost all societies, and tobacco companies look for the delicate packing of their prepared cigarettes