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Elevated levels of NGF and BDNF have been associated with nerve regeneration and repair mechanisms

Antioxidants are linked to a lower death rate from heart disease, a lower incidence of cancers of the lungs, colon, oesophagus, stomach, throat, and mouth, mouth, as well as a lower risk of premature ageing

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We speculate that interventions targeting the activation pathway of CD4 + T cell subpopulations, such as down-regulation of HIF-1 or inhibition of hypoxic microenvironment, may reduce the expansion and function of CD4 + T cells, thereby inhibiting the initiation or persistence of SLE