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The human skin is a complete steroidogenic organ, as intracrine estrogen biosynthesis occurs either from precursors of adrenal origin (dehydroepiandrosterone sulfate [DHEA-S] and DHEA) or through the conversion of cholesterol to pregnenolone and its subsequent transformation to biologically active estrogen in skin cells (Labrie et al., 2000

The absolute number of monocytes ( Supplementary Table 2 ) dropped to one fifth of the initial level immediately after LPS administration and remained at this level for 3 days, before recovering until 7 d pi

the reabsorbed amino acids are then used to effectively resynthesize GSH in hepatocytes

higher hydration and the addition of fats/oils increase extensibility