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Erastin can enhance the sensitivity of many cancer cells to various chemotherapeutic drugs and enhance the sensitivity of cancer cells to radiation

Damiani G, Bragazzi NL, Karimkhani Aksut C, Wu D, Alicandro G, McGonagle D, Guo C, Dellavalle R, Grada A, Wong P, La Vecchia C, Tam LS, Cooper KD, Naghavi M (2021) The global, regional, and national burden of psoriasis: results and insights from the global burden of disease 2019 study

Dosing is typically more potent than topical but also more controllable in terms of precise measurement

Intriguingly, despite DL reducing plaque deposition, astrocytic and microglial activation in the DL mice was comparable to AL-fed mice, while pro-inflammatory gene expression was extremely high