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Glutathione is a tripeptide naturally synthesised in the liver, where it plays a role in antioxidant defence and cellular detoxification

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For metabolomic and molecular studies, at the end of treatment (at 8 wk of age), the brains were surgically removed after cervical dislocation and stored at 80C

192 The tumor extracellular matrix (ECM), primarily composed of dense collagen fibers, hyaluronan, fibronectin, periostin, and other macromolecules, forms a physical and biochemical barrier that significantly limits the penetration and distribution of therapeutic agents, including nanoparticles, cytokines, and PRR agonists