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Neurons grown on glass coverslips were transferred to a recording chamber of an upright microscope and continuously superfused with the extracellular medium (in the presence or absence of MgSO4, according to the experimental condition)

10.1126/science.aaa0079 210 YangL.Garcia CanaverasJ

It has been observed that amyloid peptide is responsible for hydrogen peroxide accumulation within the cultures of neuroblastoma and hippocampal neurons [111, 112] probably by the direct binding of amyloid to catalase leading to decreased enzyme activities [26]