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Mussi N, Stuard Wl, Sanches JM, Robertson DM

FIGURE 1 Modulation of antioxidant levels in GK rat liver and kidney after exercise The level of GSH, an endogenous antioxidant synthesized abundantly in the liver was significantly reduced in both the liver and kidney (50%60%) of GK diabetic rats (Figure 2A)

This is a key study to suggest that IL-6 may dictate whether naive T cells differentiate into pro-inflammatory T H 17 cells or FOXP3 + T reg cells during antigen-specific priming of T cells in the peripheral immune compartment