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Differential expression profile of lipid metabolism genes in KO livers following chronic alcohol feeding Hepatic quantitative real-time PCR analysis revealed that in KO mice fed control chow diet, genes promoting lipid synthesis ( Srebp1 , Fasn , Scd1 , and Fads1 ) were suppressed (Fig

Ji and colleagues have demonstrated that the specific inhibition of HMOX1 expression significantly suppresses RPE ferroptosis, suggesting that HMOX1 may be a viable target for protecting RPE cells against blue light-induced ferroptosis (88)

Final calculations, tests for significance and graphic illustrations were performed with GraphPad Prism 10

Mitochondrial calcium uniporter blocker prevents cardiac mitochondrial dysfunction induced by iron overload in thalassemic mice