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2 Pathological role of ferroptosis in retinal diseases The retina is mainly composed of the inside out of retinal pigment epithelial cells (RPE), photoreceptor cells, horizontal cells, bipolar cells, node cells, amacrine cells, and retinal ganglion cells (RGC), as the key part of the vision with the functions that captures light and passes it to the brain (Hoon et al., 2014)