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Description

for 12 days) increased chemosensitivity of paclitaxel in Ehrlich ascites carcinoma model, where it promoted expression of tumor suppressor genes (p21, Brca1 and Hic1), induction of apoptosis-related markers (cleaved caspase-3,7 and 12 and PARP), modulation of p53 and JAK-STAT signaling and reduction of phosphorylated p65 and Akt [116]

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This was due to the fact that the system contained a large amount of silver nanoparticles, and the adsorption of glutathione onto the surface of AgNPs led to the agglomeration of silver nanoparticles and the reduction of their particle spacing, which increased the intensity of the IR absorption peak

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