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The primary strength of this approach lies in its very broad cargo compatibility, encompassing full-length proteins, glycans, nucleic acids, and synthetic molecules that resist direct genetic encoding (Brune and Howarth, 2018

Twelve (50%) patients in the proactive group and nine (36%) patients in the reactive group were at high risk of ODS

That said, we still need more detailed human studies to fully clarify these questions

Prospective studies will be needed to determine whether the observed associations reflect a direct effect of semaglutide exposure or other factors linked to treatment patterns and patient characteristics