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By the time most people are diagnosed, their bodys long-term B12 reserves (which are stored in the liver) are completely empty

[DOI] [PMC free article] [PubMed] [Google Scholar] 166.Prentice KJ, Saksi J, Hotamisligil GS

The most common form of B12 that youll find everywhere is cyanocobalamin and it is not very active or beneficial to the body because the absorption rate is fairly low, thats because the body has to convert it first into hydroxy B12, and from there the hydroxy B12 has to be converted into both adenosylcobalamin and methylcobalamin