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Clinical Implications and Future Directions Despite advances in the understanding and treatment of asthma over the past decade, asthma remains a challenging disorder associated with a significant degree of respiratory morbidity

D.Oropesa-AvilaM.VegaA

In the core region of cerebral infarction, severe ischemia and hypoxia-induced metabolic disturbances lead to an increased release and impaired reuptake of glutamate, the primary excitatory neurotransmitter of the nervous system

Based on the published literature on Nrf2, the rise of Nrf2 protein levels is likely due to impaired degradation of the Nrf2 protein, rather than an induction of its transcription or translation