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Isoquercetin has been shown to modulate the toll-like receptor 4 (TLR4) and NF-B, while the pharmacological activity of rutin revolves around inhibition of pro-inflammatory signals such as IL-6 and IL-1 signaling (Ma et al., 2018

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The expert panel debated crucial research priorities and future policies, identified gaps and untapped potential in basic health approaches that have been grossly neglected, and approved the evidence-based 101 consensus statements presented

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CRJ: data curation, writing-original draft preparation

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