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Borrelia doesn't just infect passively, it also actively disrupts the immune response

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2b) corresponding to the ZZ1-SO 2 H chemical tag and the surrounding YPEL5 residues, along with their atomic coordinates (shown as sticks)

62 UPS-targeted therapies and induced protein degradation strategies Recent advances in targeted protein degradation have transformed the ubiquitinproteasome system into a highly versatile therapeutic platform